In the war on infections, add sugar
James Collins is a Boston University bioengineer whose research on the warfare between bacteria and antibiotics has persuaded him that his illnesses in college were more than bad luck. Instead, he blames "persisters," bacteria that evade medications by slipping into a zombielike state, then mysteriously reawaken to cause new infections. In a study to be published today, Collins, 45, reports that he and colleagues have discovered how to make these bacteria, which are thought to underlie many stubborn infections, susceptible to drugs. Their solution is deliciously simple: Just add sugar. "Could we wake these guys up?'' Collins asked. "Could we . . . get them up off the ground so we can punch them and knock them out?" The answer appears to be yes. In tests in a lab dish and in mice, the sugar revved bacteria up just enough so that a particular type of antibiotic could make its way into the cells and destroy them.
- Half of All Primary Care, Internal Medicine Jobs Unfilled in 2013
- How Digital Strategy Shapes Patient Engagement at Boston Children's Hospital
- CFO Exchange: Smartphones Poised to Disrupt Healthcare, Says Topol
- CNO on Hospital Redesign: 'You Can't Over-Communicate'
- Carondelet to Pay $35M to Settle Fraud Allegations
- Some Cancer Hospitals' Quality Data Will Soon Be Public
- CA Powers Up $80M HIE to 'Create Value in the Data'
- PA Ranks See 'Phenomenal Growth,' Lack of Diversity
- 3 Traits Personality Assessments Can't Reveal
- Cleveland Clinic Partners with North Shore-LIJ for Heart Care