Even as the cost of EpiPens dramatically rose, so too did the number of prescriptions written for patients in Medicare, sending spending by the program skyrocketing nearly 1100% from 2007 to 2014, a Kaiser Health News report found. During the same period, the number of Medicare beneficiaries using EpiPens climbed 164%, from nearly 80,000 users in 2007 to more than 211,000 in 2014.