At least one of the cases is expected to be heard by the U.S. Supreme Court during its next term, which begins in October.
The ruling is viewed as an important win for the Obama administration especially since the three-judge panel was comprised of two Republican appointees and one Democratic appointee.
A statement posted on the website of the Department of Justice, which is defending the law says: "We welcome the Sixth Circuit's ruling today dismissing this challenge to the Affordable Care Act and its finding that Congress acted within its authority in passing this landmark health care reform law. We will continue to vigorously defend the health care reform statute in any litigation challenging it. Throughout history, there have been similar challenges to other landmark legislation such as the Social Security Act, the Civil Rights Act, and the Voting Rights Act, and all of those challenges failed. We believe these challenges to health reform will also fail."