Among some of the examples listed:
"When you're doing something that, psychologically, it's plausible that it could help, and you're getting reimbursed well, together that's really a strong psychological motivation to doing it," despite what the evidence says.
In an accompanying editorial, John Ioannides, MD, of the Stanford Prevention Research Center, called the NCI article impressive and said that "at a minimum, it poses major questions about the validity and clinical utility of a sizeable portion of everyday medical care."
And, he added, Prasad and colleagues "offer some hints about how this dreadful scenario might be aborted. The 146 medical reversals that they have assembled are, in a sense, examples of success stories that can inspire the astute clinician and clinical investigator to challenge the status quo and realize that doing less is more."