As the importance of exchanging patient data through health information exchanges grows, the College of Healthcare Information Management Executives (CHIME) and the eHealth Initiative have released a guide that offers practical assistance on measures to successfully implement these exchanges. The HIE Guide for CIOs is a Web-based tool that executives at CHIME and eHI hope will be used to help healthcare organizations demonstrate one of the core requirements of Stage 1 Meaningful Use, which is to electronically exchange key clinical information among providers of care and patient authorized entities.