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13 things to know about Paxlovid, the COVID-19 pill

By Yale Medicine  
   December 16, 2025

Paxlovid, an FDA-approved oral antiviral pill that can be taken at home, is the go-to treatment for COVID-19. If you are at high risk for severe disease from COVID, and you take it as soon as possible within the first five days of experiencing symptoms, it will lower your risk of getting so sick that you need to be hospitalized.

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