Frey had led AMITA Health since its creation in 2015.
AMITA Health CEO Mark Frey is leaving the Lisle, Illinois-based Catholic health system, a spokesperson confirmed Friday afternoon.
In a statement, the organization wished Frey "continued blessings in future endeavors," while adding that Karen Springer, executive vice president of performance optimization and nursing operations for Ascension, and Eddie Soler, executive vice president of finance for AdventHealth, will split the role of interim co-CEO while AMITA searches for a replacement.
Frey had led the system since its creation in 2015 following a merger between Ascension's Alexian Brothers Health System, based in Arlington Heights, Ill., and Adventist Health System, based in Hinsdale, Ill.
Frey previously served as CEO of Alexian Brothers prior to its acquisition by Ascension in 2012.
Frey's exit also comes months after Ascension CEO Anthony Tersigni, EdD, FACHE announced his retirement, effective at the end of 2019.
Last year, Ascension acquired Chicago-based Presence Health, partnering it with AMITA in a move that doubled the latter organization's hospital count.
In a statement at the time of the deal, Frey said the move would allow the system to "do even more to deliver the holistic care our patients and their families need, and do it even more efficiently."
In February, three AMITA Health facilities were named among Healthgrades' "America's Best Hospitals."
Jack O'Brien is the finance editor at HealthLeaders, a Simplify Compliance brand.