Twenty-seven minutes into a town hall with staff last week, NIH Director Dr. Jay Bhattacharya acknowledged that he was going to get into uncomfortable territory. 'This one's a tough one for me,' Bhattacharya told the audience of researchers and other NIH employees gathered in an auditorium at the biomedical research agency's headquarters in Bethesda, Maryland, last Monday, before introducing one of the most divisive topics in science.