After months of speculation, President Barack Obama announced his intent to appoint Harold Varmus, MD, as Director of the National Cancer Institute. Varmus, a former director of the National Institutes of Health, co-recipient of the 1989 Nobel Prize in Physiology or Medicine for studies of the genetic basis of cancer, and recent co-chair of President Obama's Council of Advisors on Science and Technology, has served as the president of Memorial Sloan-Kettering Cancer Center in New York City since January 2000.