Southern Illinois Healthcare and Harrisburg Medical Center have signed a letter of intent to formally consider the joining of the two organizations, according to a news release from SIH on Tuesday afternoon. Harrisburg Medical Center is a 71-bed nonprofit 501(c)(3) sole community hospital located in Harrisburg that serves Saline, Gallatin, Hardin, Pope and White counties. HMC operates clinics in Harrisburg and Eldorado, as well as a primary care clinic and a behavioral health clinic in Williamson County and two mine clinics located in Williamson and Hamilton counties.