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Weight loss drugs like Ozempic can raise low testosterone — what that means for men

By New York Post  
   July 16, 2025

Research indicates that weight loss can enhance testosterone levels because excess body fat contains the enzyme aromatase, which converts testosterone into estrogen. "While it is well-known that weight loss from lifestyle changes or bariatric surgery increases testosterone levels, the impact that anti-obesity medications may also have on these levels has not been widely studied," says Shellsea Portillo Canales, MD, an endocrinology fellow at SSM Health St. Louis University Hospital in Missouri.

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