Denver Health Medical Center will cut about 300 jobs to reduce its personnel expenses by $18 million within 12 months. Hospital officials, dealing with a deficit that reached $1 million this spring, said the job cuts will come through a combination of layoffs, attrition and a reduction in new hires across all departments. The hospital's total employment will contract by about 5 percent, to 5,400 people. Denver Health's budget, hundreds of millions of dollars, is suffering from a combination of factors including the sequester — the automatic federal trims that took effect this spring after Congress couldn't agree on a budget fix — and the lack of a profitable group or chain to financially back the hospital.