A widely-known Massachusetts anesthesiologist, whose research has influenced how doctors treat surgery patients for pain, has been accused of fabricating results in at least 21 published papers, and in some cases even inventing patients. Colleagues say the case is one the largest ever of alleged medical research fraud. Scott Reuben, MD, works at Baystate Medical Center in Springfield, and has published dozens of articles on an important and emerging area of anesthesiology involving the use of more than one type of drug to relieve post-surgical pain and foster faster recovery.