HCA Inc. has filed plans for an initial public offering of up to an estimated $4.6 billion, as the biggest hospital operator in the U.S. looks to return to the public markets. Although the amount HCA registered to sell could change by the time it prices, right now it stands as the biggest IPO in the U.S. backlog, according to data from Dealogic. The hospital chain had been planning to go public since the beginning of the year, but waited for healthcare reform legislation to pass before filing, the Wall Street Journal reports.