Since taking her post as Secretary of the Department of Health and Human Services (HHS) in 2009, Power Woman Kathleen Sebelius has arguably one of the most difficult jobs in the nation. Just named by Forbes as the 25th Most Powerful Woman in the world, she's not just at the center of one of the most controversial and immensely complicated pieces of legislation in this country – the Affordable Care Act – she's tasked with turning it into a reality. For Sebelius, this involves a nightmare of administrative challenges, particularly given that something on this scale and difficulty has never before been attempted in American history with the possible exception of Franklin Roosevelt's National Recovery Administration which the Supreme Court eventually ruled to be unconstitutional.