While progress has been made in reducing the number of heart disease-related deaths in the United States over the past three decades, preventable risk factors continue to account for half of all cardiovascular deaths, according to new research. About 610,000 Americans die of heart disease every year, accounting for one in every four deaths, according to the Centers for Disease Control and Prevention. It is the number one killer of both men and women in this country. While experts say prevention is key to reducing these numbers, a study published today in the Annals of Internal Medicine suggests the message isn't getting across to the public.