The CDC analyzed outbreaks it had investigated from 2000 to 2014 that involved 415 cases, including 65 deaths. Most of the outbreaks were in buildings with large or complex water systems, such as hotels, hospitals and long-term-care facilities. The report only looked at outbreaks associated with buildings, but the disease is also found on cruise ships. About half of outbreaks examined were the result of a single failure, such as a broken disinfection system or human error.