After nearly two decades with Columbus Regional Healthcare System, Lance Duke has resigned as president and chief executive officer of The Medical Center. The system said it plans to begin an immediate search for Duke's replacement, with new Columbus Regional CEO Chuck Stark moving his office to The Medical Center. He will handle day-to-day duties at the system's flagship hospital until a successor is found. Duke, 53, who had been with Columbus Regional since 1993, was passed over for the top position following a nationwide search that culminated with Stark's hiring.