INDIANAPOLIS (AP) — Indiana's largest hospital system said Thursday it will cut about 800 jobs and realign some services as part of a nationwide trend by large-scale providers to cut expenses and adapt to changing trends in health care. The cutbacks at Indiana University Health officials will go into effect by Dec. 1, company officials said at a news conference. Cuts will be felt at seven hospitals, including the system's Indianapolis-area hospitals and those in Muncie and Tipton. "This is going to affect every part of the organization. We don't know who exactly is going to be affected by this," said James Terwilliger, president of IU Health Methodist Hospital and IU Health University Hospital in downtown Indianapolis.