Supply-chain instability at the start of the COVID-19 pandemic had a profound effect on the healthcare industry, highlighted by the procurement crisis in Personal Protective Equipment (PPE) for frontline healthcare workers and medical equipment and pharmaceuticals for patients. Even as we begin to envision a post-pandemic future, continuing backlogs and unsustainable workarounds and rising international turmoil supply fresh evidence that supply-chain fragility is untenable. Resilience is essential.