The shutdown of a Canadian nuclear reactor that is a crucial supplier of medical scanning isotopes is interrupting care to patients and hindering suppliers. Doctors are worried the Ontario-based plant, run by Atomic Energy of Canada Ltd., could be down for a prolonged stretch or may never restart. Either scenario would further snarl a supply line running through Cardinal Health Inc., MDS Inc.'s Nordion unit and privately held Lantheus Medical Imaging Inc., among other companies.