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UCI Health lays off 150 workers as part of restructuring

By The Orange County Register  
   March 24, 2026

UCI Health, which just opened a new hospital with 970 new employees in Irvine four months ago, plans to lay off 150 healthcare workers as part of a restructuring throughout its system. UCI Health is joining a wave of other hospitals across the state that have collectively laid off thousands of employees over the past year because they’ve been stripped of billions of dollars in federal and state funding for health care. The catalyst for the cuts is coming from the passage of the One Big Beautiful Bill Act, or HR 1, signed into law last summer by President Donald Trump. The layoffs at UCI Health include a mix of operational, administrative and support functions across the organization, and affect 1% of the system's 14,200 employees.

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